Aloha Reader,

Is osteoporosis caused by gut dysbiosis?

You bet it is!

Check out this article: Gut Microbiome and Osteoporosis or this article: The gut microbiota in osteoporosis: dual roles and therapeutic prospects​

​See below to read what AI had to say about it. Its a nice summary.

Next week in my new osteoporosis class we are going to explore how gut dysbiosis and osteoporosis are linked and what to do about it. I'd love for you to join me!

Here is a link to the first class in the six week series. It is my gift to you.

If you enjoy the class join me next week. I've extended the registration for a few more days! The link above is good until next Wed.

Hope to see you in class!

​Register now for the next Micro Moves series focusing on osteoporosis​

Most people think that taking a bunch of calcium and lifting heavy weights will help prevent and resolve osteoporosis. That is far from the truth!

In this upcoming 6 week series we will focus on osteoporosis and fall prevention. Not only will we learn a sequence of exercises to prevent and resolve osteoporosis, but we will explore lifestyle factors such as diet, rest, exercise, sun exposure, the microbiome, proper supplementation, and many other contributors to prevent and resolve osteoporosis.

Micro Moves Osteoporosis Group Class November 2025

STOP SUFFERING FROM PAIN AND START FEELING FREE, POWERFUL, AND STRONG!

Micro Moves group class six week series addresses the deep stabilizers of your core body. 75% of your muscles are deep stabilizers.

In this flowing follow along group class we will learn a series of short movements- exercises- choreographed by Lisa Orig that will not only give us a movement experience of all of our deep stabilizing muscles, but can potentially enhance our dynamic stability, mobility, control, coordination, and readiness to move our body safely in all directions.

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WHAT DO YOU GET WHEN YOU ENROLL IN MICRO MOVES GROUP CLASS June 2025?

• 6 Educational Online Movement Lessons so that you can learn and practice the principles to resolve your bodily issues and strengthen your deep core muscles.
  • Value: $400

FEE: $252.00

Please note: We do not offer refunds after registration.

DATES: November 12th – December 17th, 2025

TIME: WEDNESDAYS 3 pm HST - 3:55 pm HST via Zoom. Recordings will be available for 7 days after the class if you are unable to attend live.

Below is what AI had to say about: Is osteoporosis caused gut dysbiosis?​

References in the link.

Emerging evidence strongly suggests that gut dysbiosis is a significant contributing factor to the development and progression of osteoporosis, although it is not the sole cause. Research indicates that patients with osteoporosis exhibit pronounced gut microbiota dysbiosis, characterized by reduced microbial diversity and altered abundances of specific bacterial taxa. For instance, studies have found elevated levels of Bacteroidetes, Bacteroides, Eisenbergiella, Clostridium, Lactobacillus, and Eggerthella, alongside increased Parabacteroides and Flavobacterium, while Ruminococcus is significantly decreased. Notably, a lower Firmicutes/Bacteroidetes ratio is associated with osteoporosis, and Actinobacteria have been positively correlated with bone mineral density.

The causal relationship between gut dysbiosis and osteoporosis has been demonstrated in animal models. A study using fecal microbiota transplantation (FMT) from senile osteoporotic rats to young rats induced osteoporosis in the recipients, evidenced by increased bone resorption markers and decreased bone volume, alongside impaired intestinal barrier function. This indicates that dysbiosis can directly contribute to bone loss.

The mechanisms linking gut dysbiosis to osteoporosis involve multiple pathways along the gut–bone axis. Dysbiosis can promote systemic inflammation and immune dysregulation, leading to a Th17/Treg imbalance and increased osteoclastogenesis. Pathogenic bacteria and their metabolites, such as lipopolysaccharide (LPS), inhibit osteoblast maturation and promote osteoclast activation, while beneficial metabolites like short-chain fatty acids (SCFAs), particularly butyrate produced by bacteria such as Faecalibacterium, stimulate osteoblast differentiation and bone formation. Dysbiosis also impairs intestinal barrier integrity, allowing bacterial products to enter circulation and trigger inflammatory responses that negatively impact bone metabolism.

Furthermore, microbial metabolites influence endocrine pathways critical for bone health, including estrogen, serotonin, and parathyroid hormone (PTH). The gut microbiota also affects calcium absorption through SCFA production, which lowers gut pH and enhances mineral uptake. Despite these well-documented associations and mechanistic insights, the precise causal pathways and the full therapeutic potential of targeting the gut microbiome remain under investigation. While dysbiosis is a key modifiable factor, osteoporosis is a multifactorial disorder influenced by genetics, age, sex, and lifestyle, with gut dysbiosis acting as a significant contributing element within this complex interplay.

REMEMBER, self care is health care! If you don't care for yourself you won't be able to care for anyone else.

Have a beautiful day!

Lisa